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The film gives a portrait of mental health treatment during the 50s, which was the heyday of treating mental patients in big institutions.
Due to a possible cholera epidemic onboard, passengers on a ship are forced to disembark at Pago Pago, a small village on a Pacific island where it incessantly rains. Among the stranded passengers are Sadie Thompson, a prostitute, and Alfred Davidson, a fanatic missionary who will try to redeem her.
Trapped on a remote island by a hurricane, a group discover a doctor has been experimenting on creating half sized humans. Unfortunately, his experiments have also created giant shrews, who when they have run out of small animals to eat, turn on the humans.
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