Cornelius, a Roman Centurion, and follower of the Jewish faith, had a vision of an angel who told him to find Simon Peter and bring him back. Since Peter believed Gentiles were unclean, he should not go. He thought this was a test. But after a discussion with God, Peter realized neither people or food are inherently unclean, so he went to Cornelius and many gentiles were saved and baptized both in water and the Holy Spirit.

Paul here is in Ephesus, and he asks some disciples if they received the Holy Spirit. The answered they never heard of this, so Paul lays hands on them and they receive the Holy Spirit. Some Jewish exorcists attempted to use Jesus' name to cast out demons. However, a demon said they heard of Paul and Jesus, but not them. They were then pounced on them and injured them. Then a riot occurred on Ephesus. They held back Paul from going to them, but several of hi friends did go. But when the croud brought them before the town clerk, but since they did not do anything illegal, he let them go.

Some Jews began teaching that Gentiles could not be saved unless they were circumcised. Paul and Barnabas challenged them, and ultimately this dispute was brought before the Church in Jerusalem where the decision was made stating circumcision was not required due to references in the Old Testament, which presentated by James. Paul, who was in Antioch, spoke with Barnabas regarding meeting with the bretheren in all the cities the ministered in, to see how they were doing. Barnabas wanted to take John Mark with them, but Paul said no, so Mark went with Barnabas and Silas went with Paul.