The Stooges are key witnesses at a murder trial. Their friend Gail Tempest, who dances at the Black Bottom cafe where the Stooges are musicians, is accused of killing Kirk Robin.

A social worker who recently lost her husband investigates the strange Wadsworth family. The Wadsworth's might not seem too unusual consisting of the mother, two grown daughters and the diaper-clad, bottle-sucking baby. The problem is, the baby is twenty-one years old.

For as long as crime boss Albert Mendoza (Everett Sloane) has been running a notorious ring of hired hit men, District Attorney Martin Ferguson (Humphrey Bogart) has been hunting him down. But Ferguson cuts a deal with Mendoza's henchman Joe Rico (Ted De Corsia), and the mob boss is finally arrested. However, Rico dies mysteriously before he can testify against Mendoza.