A mouse is annoying the family of Mr. and Mrs. Evil J. Evil, the scientists, and Snagglepuss is offered food and lodging if he will get rid of the pest. The trouble is that the Evil's little boy has been experimenting with the mouse, and the furry rodent is now six feet tall!

Snagglepuss adds a room to his house, hoping the rent he receives will finance a vacation trip to the South Seas. Lovely Lila, a Southern belle, becomes his new tenant. In no time, Snagglepuss finds himself moved into the spare room and Lila has the run of the house. When she demands new drapes, new decorating, and not one but two swimming pools, Snagglepuss rebels.

The Pink Panther joins the army and keeps angering his sergeant (the Little Man) with his usual antics.