Snagglepuss escapes from his cage, dons a Southern gambler's costume and mingles with passengers aboard the SS St. Louis Lou.

Lorelei Lee is a beautiful showgirl engaged to be married to the wealthy Gus Esmond, much to the disapproval of Gus’ rich father. When Lorelei goes on a cruise accompanied only by her best friend, Dorothy Shaw, Esmond Sr. hires a private detective, to follow her and report any questionable behavior that would disqualify her from the marriage.