Lorelei Lee is a beautiful showgirl engaged to be married to the wealthy Gus Esmond, much to the disapproval of Gus’ rich father. When Lorelei goes on a cruise accompanied only by her best friend, Dorothy Shaw, Esmond Sr. hires a private detective, to follow her and report any questionable behavior that would disqualify her from the marriage.

When perennial college students Danny O'Neill and Hank Taylor are forced to make it on their own, the competitive pair get jobs with Artie Shaw's band and reunite with ex-manager Ellen Miller.

Tough narcotics detective ‘Popeye’ Doyle is in hot pursuit of a suave French drug dealer who may be the key to a huge heroin-smuggling operation.