Snagglepuss adds a room to his house, hoping the rent he receives will finance a vacation trip to the South Seas. Lovely Lila, a Southern belle, becomes his new tenant. In no time, Snagglepuss finds himself moved into the spare room and Lila has the run of the house. When she demands new drapes, new decorating, and not one but two swimming pools, Snagglepuss rebels.

The film argues that sexually explicit materials corrupt young viewers and readers, leading to acts of violence and perverted attitudes regarding sex—including inclination toward homosexuality. Perversion for Profit was serious in its suggestion that pornography could erode the integrity of American culture.