Flip the Frog is a soda jerk who serves movie stars, but one of his concoctions changes an effeminate man into Mr. Hyde.

Herman (a mouse) and Henry (a rooster) notice a poster that will award $1,000 to anyone who will stay in the ring for one round against a champion boxing rooster. Herman goes to Henry, who is feeling really low about himself, as he is getting bossed and pushed around by his wife. One thing leads to another, and the scrawny Henry is going up against the Champ.