Snagglepuss finds a missing baby and goes to the address where the baby lives to collect the reward. But it is the lion-hating Major Minor's baby and the Major gets out his hunting rifle to reward Snagglepuss with a bullet. Snagglepuss has difficulty trying to avoid the Major because the baby knows all Snag's hiding places and leads the Major to them.

When half-breed Indian Yaqui Joe robs an Arizona bank, he is pursued by dogged lawman Lyedecker. Fleeing to Mexico, Joe is imprisoned by General Verdugo, who is waging a war against the Yaqui Indians.